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Otolaryngology, ENT & Sinus News Provided by Dallas ENTNasal irrigation with or without drugs: the evidenceDecember 8, 2011, 5:00 am by Current Opinion in Otolaryngology & Head and Neck SurgeryPurpose of review: To review the recent literature of nasal irrigations with or without drugs, including delivery systems, nasal saline, antibiotics, antifungals, steroids, surfactants, and interleukin (IL)-5 modulators, for the treatment of chronic rhinosinusitis (CRS). Recent findings: As antibiotic resistance increases in CRS, culture-directed, rather than empiric, topical antibiotics are increasingly critical in optimal treatment. Topical irrigation with mupirocin significantly reduces Staphylococcus aureus biofilm mass in vitro. Surfactants and humanized anti-IL-5 monoclonal antibody are novel therapies demonstrating promising results in CRS. Summary: Physiologic saline irrigation is beneficial in the treatment of symptoms of CRS. Low-level evidence supports the effectiveness of topical antibiotics in the treatment of CRS. The use of topical antifungals is not supported by the majority of studies. Intranasal steroids are beneficial in the treatment of CRS with nasal polyposis. There is insufficient evidence to demonstrate a clear overall benefit for topical steroids in CRS without nasal polyposis. (C) 2011 Lippincott Williams & Wilkins, Inc.
More from Current Opinion in Otolaryngology & Head and Neck Surgery Editorial introductions Current Opinion in Otolaryngology & Head and Neck Surgery: May 31, 2012, 6:00 am No abstract available Practical clinical management strategies for the allergic patient with chronic rhinosinusitis Current Opinion in Otolaryngology & Head and Neck Surgery: May 31, 2012, 6:00 am Purpose of review: Allergic rhinitis often coexists with chronic rhinosinusitis (CRS). The purpose of this review is to provide a practical algorithm for the treatment of patients with allergic rhinitis and CRS. Recent Surgical options for the allergic rhinitis patient Current Opinion in Otolaryngology & Head and Neck Surgery: May 31, 2012, 6:00 am Purpose of review: Allergic rhinitis is a very common disorder that affects millions of patients annually and the hallmark complaint of nasal obstruction significantly impacts the quality of life. Many surgical options Beyond voice: perceptions of gender in male-to-female transsexuals Current Opinion in Otolaryngology & Head and Neck Surgery: May 31, 2012, 6:00 am Purpose of review: This review covers recent research findings that demonstrate the effectiveness of speech pathology intervention in enabling male-to-female transsexual individuals to portray their gender identity through speech. Research reports that Speech therapy and rehabilitation Current Opinion in Otolaryngology & Head and Neck Surgery: May 31, 2012, 6:00 am No abstract available
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